09:30 - 12:30, 3 hours, International Conference Hall
Plenary Session 4
Medical Aspects: Surveillance and Treatment of Asbestos-related Diseases
4-A: Asbestos and Non-asbestos Agents in Mesothelioma Pathogenesis and Immunology
Chairs: Yasunosuke Suzuki and Iguchi Hiroshi
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Takemi Ohtsuki
Department of Hygiene, Kawasaki Medical School
ABSTRACT:
The HTLV-1 immortalized human polyclonal T cell line, MT-2, was continuously exposed to low doses of chrysotile-B (CB) for more than half a year to estimate the long-term cell biological effects of silicate on the human T lymphocytes. The appearance of apoptosis, production of cytokines and expression of several genes will be discussed.